Could probiotics from your donor fix gut problems after transplant?

NCT ID NCT07188909

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early study tests whether probiotics made from the patient's own or their donor's gut bacteria can improve intestinal health in people with acute graft-versus-host disease (aGVHD) after a stem cell transplant. Ten participants over age 50 will take probiotic capsules and be monitored for changes in stool frequency and gut bacteria. The goal is to see if this approach can ease symptoms and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Patient-donor derived probiotics

What this could lead to

If it works, this could point toward a simple probiotic treatment to ease gut symptoms and improve quality of life after stem cell transplant.

What could go wrong

This is a very small, early study with only 10 people, so results may not apply widely. The approach is experimental and may not improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

    Tianjin, Tianjin Municipality, 300020, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••