Could probiotics from your donor fix gut problems after transplant?
NCT ID NCT07188909
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early study tests whether probiotics made from the patient's own or their donor's gut bacteria can improve intestinal health in people with acute graft-versus-host disease (aGVHD) after a stem cell transplant. Ten participants over age 50 will take probiotic capsules and be monitored for changes in stool frequency and gut bacteria. The goal is to see if this approach can ease symptoms and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Patient-donor derived probiotics
- What this could lead to
- If it works, this could point toward a simple probiotic treatment to ease gut symptoms and improve quality of life after stem cell transplant.
- What could go wrong
- This is a very small, early study with only 10 people, so results may not apply widely. The approach is experimental and may not improve outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Tianjin, Tianjin Municipality, 300020, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a lung protein tame severe graft-versus-host disease?
- Combination drug approach aims to tame immune attack after stem cell transplant
- New shot may shield transplant patients from deadly immune attack
- New drug shows promise in controlling transplant complications
- Poop pills may tame deadly transplant complication
- JAKAVI under the microscope: new study tracks GVHD treatment in real life