Gut bacteria supplement could tame high uric acid

NCT ID NCT07613164

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a probiotic-uricase supplement can safely lower uric acid levels in people with hyperuricemia. 45 adults will take the supplement for 2 weeks, and researchers will track changes in uric acid, gut bacteria, and related metabolites. The goal is to see if this oral supplement could be a new way to manage high uric acid and gout.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Probiotic-uricase complex preparation (dietary supplement)
What this could lead to
If it works, this could point toward a simple, oral supplement to help manage high uric acid and reduce gout risk.
What could go wrong
This is a very small, early exploratory study with only 45 people. It is not yet recruiting, and results may not lead to a proven treatment. The supplement is taken for just 2 weeks, so long-term effects are unknown.

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Conditions

The condition(s) this trial relates to.

gout Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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