Good bacteria cream could be new acne weapon

NCT ID NCT07366229

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a cream made from a common probiotic, Lactobacillus reuteri, that has been coated with a special material to help it survive on the skin. The goal is to see if it can rebalance the skin's bacteria and reduce acne. About 196 people with mild to moderate acne will use the cream nightly for 2 weeks and be followed for 8 weeks. The cream is compared to plain probiotic cream, a placebo, and a standard acne treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

engineered Lactobacillus reuteri cream with a zinc sulfate-tannic acid coating

What this could lead to

If it works, this could offer a new, natural-seeming acne treatment that targets skin bacteria instead of using harsh chemicals.

What could go wrong

This is a small, early-phase trial. The probiotic cream may not work better than existing treatments, and the coating's effect on skin is still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acne Acne Vulgaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shenzhen People's Hospital

    RECRUITING

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••