Massive study aims to unlock secrets of immune system diseases

NCT ID NCT03394053

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study aims to learn more about primary immunodeficiency disorders (PIDs), which weaken the immune system and make people more prone to infections. Researchers will compare genetic and health data from people with PIDs, their healthy relatives, and healthy volunteers to find genetic causes and new disease patterns. Up to 2,500 participants aged 0 to 90 will be followed for up to 10 years with annual check-ins and blood draws.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY IMMUNODEFICIENCY DISORDERS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's National Health System (CNHS)

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States