Blood-derived face cream boosts skin moisture and elasticity in small trial

NCT ID NCT07359924

Completed Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a face cream containing platelet-rich fibrin (PRF), made from a person's own blood, to see if it could improve skin aging. Twenty healthy adults aged 20-40 applied three different creams to their faces daily for four weeks. The PRF cream improved skin hydration, elasticity, and barrier function more than a plain cream or one with added growth factor. The results suggest PRF creams are safe and effective, but larger and longer studies are needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich fibrin (PRF) cream
What this could lead to: If it works, this could lead to a natural, safe anti-aging cream that improves skin hydration and elasticity without harsh chemicals.
What could go wrong: This was a small, short-term study on 20 healthy people, so results may not apply to everyone. The cream uses a person's own blood components, which requires preparation and may not be widely available.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SKIN AGEING

Contacts and locations

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Locations

Poznan University of Medical Sciences

Poznan, The Greater Poland, 60-812, Poland

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