Blood-derived face cream boosts skin moisture and elasticity in small trial
NCT ID NCT07359924
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a face cream containing platelet-rich fibrin (PRF), made from a person's own blood, to see if it could improve skin aging. Twenty healthy adults aged 20-40 applied three different creams to their faces daily for four weeks. The PRF cream improved skin hydration, elasticity, and barrier function more than a plain cream or one with added growth factor. The results suggest PRF creams are safe and effective, but larger and longer studies are needed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- platelet-rich fibrin (PRF) cream
- What this could lead to
- If it works, this could lead to a natural, safe anti-aging cream that improves skin hydration and elasticity without harsh chemicals.
- What could go wrong
- This was a small, short-term study on 20 healthy people, so results may not apply to everyone. The cream uses a person's own blood components, which requires preparation and may not be widely available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
20 people
The number who actually took part.
- Started
-
Feb 2022
- Finished
-
Feb 2023
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 40 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy volunteers with healthy skin, who sign an agreement for study participation Exclusion Criteria: * systemic diseases, smoking, blood disorders, acute viral infections and skin inflammations, pregnancy, and breastfeeding.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Poznan University of Medical Sciences
Poznan, The Greater Poland, 60-812, Poland
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