New hope to shield transplant patients from dangerous immune attack

NCT ID NCT07440654

Summary

This study is testing whether adding a new drug called gecacitinib to standard treatment can better prevent a dangerous immune reaction called acute Graft-Versus-Host Disease (aGVHD) in patients with myelofibrosis. It will involve 40 adults with advanced myelofibrosis who are receiving a stem cell transplant from a donor. The main goal is to see if this combination lowers the rate of severe aGVHD, which can damage organs and be life-threatening.

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Contacts and locations

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