Antihistamine may shield kids from transfusion danger during heart surgery
NCT ID NCT07536152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a single dose of an antihistamine (chlorpheniramine) right after heart-lung machine use can prevent sudden low blood pressure caused by blood transfusions in children having heart surgery. Forty children with congenital heart defects will be randomly assigned to receive either the antihistamine or a placebo. The goal is to see if this simple step can make surgery safer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Misr Universty for Scince and Technology
RECRUITINGGiza, October, 12582, Egypt
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