Antihistamine may shield kids from transfusion danger during heart surgery

NCT ID NCT07536152

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving a single dose of an antihistamine (chlorpheniramine) right after heart-lung machine use can prevent sudden low blood pressure caused by blood transfusions in children having heart surgery. Forty children with congenital heart defects will be randomly assigned to receive either the antihistamine or a placebo. The goal is to see if this simple step can make surgery safer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease Transfusion Reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Misr Universty for Scince and Technology

    RECRUITING

    Giza, October, 12582, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••