New surgery aims to stop phantom limb pain before it starts
NCT ID NCT06719245
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 31 times
Summary
This study compares two ways of handling nerves during leg amputation to see which better prevents long-term pain. About 200 adults having a leg amputation due to blood vessel disease will be randomly assigned to either standard nerve cutting or a newer technique called targeted muscle reinnervation (TMR). Participants will report their pain levels and quality of life through online questionnaires over one year after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alrijne Zorggroep
NOT_YET_RECRUITINGLeiderdorp, South Holland, 2353 GA, Netherlands
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Amsterdam University Medical Center
NOT_YET_RECRUITINGAmsterdam, North Holland, 1105 AZ, Netherlands
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Erasmus Medical Center
NOT_YET_RECRUITINGRotterdam, South Holland, 3015 GD, Netherlands
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Haaglanden Medisch Centrum
NOT_YET_RECRUITINGThe Hague, South Holland, 2512 VA, Netherlands
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Isala Zwolle
NOT_YET_RECRUITINGZwolle, Overijssel, 8025 AB, Netherlands
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Leiden University Medical Center
RECRUITINGLeiden, South Holland, 2333 ZA, Netherlands
Contact
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University Medical Center Utrecht
NOT_YET_RECRUITINGUtrecht, Utrecht, 3584 CX, Netherlands
Conditions
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