Hearing shield: new drug may protect Kids' ears during cancer treatment

NCT ID NCT05756660

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 27 times

Summary

This study tests whether a drug called sodium thiosulfate can prevent hearing loss in children and young adults (ages 1 month to 39 years) who are receiving cisplatin chemotherapy for relapsed or hard-to-treat liver tumors and other embryonal cancers. Participants will get cisplatin with or without an additional drug (vorinostat). The main goal is to see if the hearing protection works, while also checking how well the tumors respond. The trial is currently on hold.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OTOTOXICITY, DRUG-INDUCED are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.