Ear shot may shield cancer patients from Chemo-Induced deafness

NCT ID NCT07281508

First seen Jan 04, 2026 · Last updated May 04, 2026 · Updated 19 times

Summary

This study tests whether injecting a medicine called sodium thiosulfate into the middle ear before each round of cisplatin chemotherapy can prevent hearing loss. About 100 adults with head and neck cancer will receive the injection in one ear only, and the treated ear will be compared to the untreated ear. The goal is to protect hearing without affecting the cancer treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Antoni van Leeuwenhoek

    RECRUITING

    Amsterdam, North Holland, 1066CX, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Erasmus Universitair Medisch Centrum Rotterdam

    NOT_YET_RECRUITING

    Rotterdam, South Holland, 3015GD, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Leiden University Medical Center

    RECRUITING

    Leiden, South Holland, 2333ZA, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stichting Radboud University Medical Center

    NOT_YET_RECRUITING

    Nijmegen, 6525GA, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Medical Center Utrecht

    NOT_YET_RECRUITING

    Utrecht, Utrecht, 3584CX, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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