Blood 'Photo' therapy may stop transplant rejection
NCT ID NCT03204721
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study tested whether a procedure called extracorporeal photopheresis (ECP) could prevent graft-versus-host disease (GVHD) in 158 patients receiving stem cell transplants for blood cancers. ECP involves removing white blood cells, treating them with a light-sensitive drug and UV light, then returning them to the patient. The goal was to reduce GVHD, a common and serious complication where donor cells attack the patient's body.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Tobias Gedde-Dhl
Oslo, Norway
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
extracorporeal photopheresis (ECP) with 8-methoxypsoralen and ultraviolet A light
What this could lead to
If it works, this could offer a way to prevent a serious complication of stem cell transplants, improving survival and quality of life.
What could go wrong
This is a completed study, but results are not yet widely confirmed. The approach is complex and may not work for everyone, and there are risks from the procedure itself.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.