New combo therapy aims to stop eye muscle disease from spreading
NCT ID NCT06342544
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times
Summary
This study tests whether starting steroids right away, followed by rituximab if symptoms return, can prevent eye muscle weakness from spreading to other muscles in people with ocular myasthenia gravis. About 128 adults diagnosed within the last 6 months will be randomly assigned to either standard care or this proactive treatment plan. The goal is to see if this approach reduces the risk of severe, generalized muscle weakness over 2 years.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHNO
ACTIVE_NOT_RECRUITINGParis, 75012, France
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Centre Hospitalier Sainte Anne
ACTIVE_NOT_RECRUITINGParis, 75014, France
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Centre Hospitalier Universitaire De Bordeaux
RECRUITINGBordeaux, 33000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Hospitalier Universitaire De Lille
RECRUITINGLille, 59037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Hospitalier Universitaire De Nice
RECRUITINGNice, 06000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Centre Hospitalier Universitaire De Toulouse
ACTIVE_NOT_RECRUITINGToulouse, 31300, France
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Fondation Adolphe de Rothschild
RECRUITINGParis, 75019, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospices Civils De Lyon
RECRUITINGLyon, 69500, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpital Raymond Pointcarre
NOT_YET_RECRUITINGGarches, 92380, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hôpital de la Pitié-Salpêtrière
NOT_YET_RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Les Hopitaux Universitaires De Strasbourg
RECRUITINGStrasbourg, 67098, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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