New strategy aims to stop eye muscle disease from spreading

NCT ID NCT06342544

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether starting steroids right away, and adding rituximab if symptoms return, can prevent eye muscle weakness from spreading to other muscles in people with ocular myasthenia gravis. About 128 adults with recent diagnosis will be followed for 2 years. The goal is to reduce the risk of severe generalized weakness that often requires long-term medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHNO

    ACTIVE_NOT_RECRUITING

    Paris, 75012, France

  • Centre Hospitalier Sainte Anne

    ACTIVE_NOT_RECRUITING

    Paris, 75014, France

  • Centre Hospitalier Universitaire De Bordeaux

    RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier Universitaire De Lille

    RECRUITING

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier Universitaire De Nice

    RECRUITING

    Nice, 06000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier Universitaire De Toulouse

    ACTIVE_NOT_RECRUITING

    Toulouse, 31300, France

  • Fondation Adolphe de Rothschild

    RECRUITING

    Paris, 75019, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospices Civils De Lyon

    RECRUITING

    Lyon, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Raymond Pointcarre

    NOT_YET_RECRUITING

    Garches, 92380, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital de la Pitié-Salpêtrière

    NOT_YET_RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Les Hopitaux Universitaires De Strasbourg

    RECRUITING

    Strasbourg, 67098, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact