New strategy aims to protect transplanted kidneys from devastating disease recurrence

NCT ID NCT03763643

Summary

This small, early study tested if a combination treatment given around the time of a kidney transplant could prevent a serious kidney disease called FSGS from coming back. It involved 21 children and adults with FSGS who were getting a transplant. Researchers compared giving plasmapheresis (a blood-cleaning process) alone to giving plasmapheresis plus a drug called rituximab, to see which was better at preventing the disease from damaging the new kidney.

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Contacts and locations

Locations

  • Children's Hospital of Colorado

    Aurora, Minnesota, 80045, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital

    Cincinnati, Ohio, 45229, United States

  • Duke University

    Durham, North Carolina, 27708, United States

  • Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • University of Alabama

    Tuscaloosa, Alabama, 35487, United States

  • University of California at Davis

    Davis, California, 95616, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45221, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.