New study aims to stop Kids' Post-Anesthesia agitation

NCT ID NCT07427446

Recruiting now Symptom relief Sponsor: Kasr El Aini Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two different drug combinations given before anesthesia to prevent emergence delirium—a state of confusion and agitation—in children undergoing heart catheterization. Fifty children will be randomly assigned to receive either dexmedetomidine plus midazolam or ketamine plus midazolam. The goal is to see which combination reduces delirium better, helping kids wake up more calmly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine and Midazolam, or Ketamine and Midazolam
What this could lead to: If it works, this could point toward a better way to prevent confusion and agitation in children after anesthesia.
What could go wrong: This is a small, early-phase study with only 50 children, so results may not apply to all kids. Both drug combos have side effects like drowsiness or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium delirium prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMERGENCE DELIRIUM

Contacts and locations

Locations

Kasralainy Hospital
RECRUITING

Cairo, Egypt

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