Can a single shot stop dialysis blood pressure crashes?
NCT ID NCT05297786
First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times
Summary
This study tests whether a drug called lanadelumab can prevent sudden drops in blood pressure that often happen during hemodialysis. The trial involves 28 adults on long-term dialysis who are prone to these episodes. Participants receive either the drug or a placebo injection, and researchers monitor blood pressure changes and the number of hypotensive events.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lanadelumab (Takhzyro)
What this could lead to
If it works, this could offer a new way to prevent blood pressure drops during dialysis, making treatment safer and more comfortable for kidney patients.
What could go wrong
This is a small, early-phase trial with only 28 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States