Hospital trial aims to stop deadly c. diff before it starts

NCT ID NCT05389904

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a prevention bundle for hospital patients who carry C. difficile bacteria but have no symptoms. The bundle includes enhanced room cleaning and special precautions. Researchers hope to prevent these carriers from developing active infections and spreading the bacteria to others. The study enrolls 300 patients in ICU or oncology units.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

prevention bundle (enhanced cleaning, precautions)

What this could lead to

If it works, this could reduce hospital-acquired C. difficile infections and deaths by catching carriers early.

What could go wrong

This is a small, early-stage trial (300 patients) testing a bundle of measures, not a new drug. Results may not apply to all hospitals or patient groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis nosocomial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact