Drug trial aims to shield cancer Patients' brains from powerful Treatment's side effects
NCT ID NCT04205838
Summary
This study tested if a drug called anakinra could prevent severe brain swelling (a condition called ICANS) in patients with aggressive lymphoma receiving a powerful treatment called CAR-T cell therapy. The goal was to see if giving anakinra when early signs of swelling appeared could stop it from becoming severe. The trial was terminated early and enrolled 23 participants who had lymphoma that returned or did not respond to other treatments.
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Contacts and locations
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Locations
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UC Davis Comprehensive Cancer Center
Davis, California, 95817, United States
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UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095, United States
Conditions
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