Choice of location may boost HIV prevention persistence

NCT ID NCT07335289

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether letting people choose where they get their follow-up HIV prevention injections (home, community, or clinic) helps them stick with the treatment. 400 HIV-negative adults in Massachusetts will receive the same-day injectable drug lenacapavir and be randomly assigned to either standard clinic follow-up or a choice of location. The main goal is to see if offering choice improves persistence at 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lenacapavir injection

What this could lead to

If successful, this could show that offering flexible follow-up locations (home, community, or clinic) helps more people stay on long-acting HIV prevention, making it easier to scale up.

What could go wrong

This is an implementation trial, not a test of the drug itself. It is early-stage and small (400 people), so results may not apply broadly. The study hasn't started recruiting yet.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital Sexual Health Clinic

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact