A pill a day: testing a new shield against HIV for women

NCT ID NCT03058835

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study looks at whether US women at risk for HIV can and will take Truvada, a daily pill that prevents HIV infection. Researchers will measure how well women stick to the pill regimen over 24 weeks and explore their attitudes toward this prevention method. The goal is to see if this approach is practical and acceptable for women in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Truvada (tenofovir disoproxil and emtricitabine) tablets taken daily as pre-exposure prophylaxis
What this could lead to
If successful, this could show that daily PrEP is a practical and acceptable way to reduce HIV risk in US women, potentially expanding its use.
What could go wrong
This is a demonstration project, not a large efficacy trial, so results may not apply broadly. Adherence may be lower than hoped, and side effects or access barriers could limit real-world use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University

    Atlanta, Georgia, 30322, United States

  • New Jersey Medical School Clinical Research Center

    Newark, New Jersey, 07103, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • West Virginia University

    Morgantown, West Virginia, 26505, United States

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