Chemo-Free hope: new combo before lung surgery shows promise

NCT ID NCT07231575

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new approach for people with early-stage lung cancer who cannot or will not take chemotherapy. Before surgery, patients receive a short course of focused radiation (SBRT) combined with immunotherapy (tislelizumab) and an antiangiogenic drug (anlotinib). The goal is to see if this chemo-free combination can shrink or eliminate the tumor safely. About 39 adults with stage IB to IIIB non-small cell lung cancer that does not have certain gene mutations will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.