Scientists investigate whether prenatal steroid treatment impacts Children's minds years later

NCT ID NCT02795871

Summary

This study aimed to understand whether a steroid treatment (dexamethasone) given during pregnancy to prevent genital development issues in girls with congenital adrenal hyperplasia (CAH) affects children's thinking, memory, and emotions later in life. Researchers followed 354 children aged 6 to 15, including those who received the treatment and their siblings, to compare their cognitive and emotional development. The goal was to gather clear evidence to help doctors decide if the benefits of this prenatal treatment outweigh potential risks to a child's brain development.

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Contacts and locations

Locations

  • Groupement Hospitalier Est - Laboratoire d'endocrinologie moléculaire et maladies rares - Centre de biologie et de pathologie Est. 59 boulevard Pinel

    Bron, 69677, France

  • Service d'endocrinologie pédiatrique, CHRU de Lille

    Lille, France

  • Service d'endocrinologie pédiatrique, CHU de Besançon

    Besançon, France

  • Service d'endocrinologie pédiatrique, CHU de Bordeaux

    Bordeaux, France

  • Service d'endocrinologie pédiatrique, CHU de Grenoble

    Grenoble, France

  • Service d'endocrinologie pédiatrique, CHU de Nantes

    Nantes, France

  • Service d'endocrinologie pédiatrique, CHU de Nice

    Nice, France

  • Service d'endocrinologie pédiatrique, CHU de Reims

    Reims, France

  • Service d'endocrinologie pédiatrique, Hopital de la Timone, APHM

    Marseille, France

  • Service d'endocrinologie pédiatrique, Hôpital Armand Trousseau, AP-HP

    Paris, France

Conditions

Explore the condition pages connected to this study.