Can a nerve pain drug ease chronic pelvic pain?
NCT ID NCT00371033
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed Phase 3 trial tested whether pregabalin, a drug used for nerve pain, can reduce symptoms in men with chronic prostatitis/chronic pelvic pain syndrome. 324 participants received either pregabalin or a placebo for 6 weeks. The main goal was to see if pain scores improved significantly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pregabalin
- What this could lead to
- If it works, this could provide a new pain-relief option for men with chronic pelvic pain.
- What could go wrong
- This trial is already completed, so results are known. Pregabalin may not significantly reduce pain compared to placebo, and side effects like dizziness or drowsiness are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Charles R Drew University of Medicine & Science
Los Angeles, California, 90059, United States
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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David Geffen School of Medicine at UCLA
Los Angeles, California, 90095-1738, United States
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Harvard Medical School
Boston, Massachusetts, 02115, United States
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Northwestern University Feinberg School of Medicine
Chicago, Illinois, 60611, United States
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Queen's University
Kingston, Ontario, K7L 2V7, Canada
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Stanford University Medical Center
Stanford, California, 94305-5118, United States
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Temple University School of Medicine
Philadelphia, Pennsylvania, 19140, United States
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University of Maryland
Baltimore, Maryland, 21201, United States
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University of Mississippi Medical Center
Jackson, Mississippi, 39216, United States
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University of Washington Harborview Medical Center
Seattle, Washington, 98108, United States
More trials for these conditions
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