Gene clues may explain higher preeclampsia risk in egg donor pregnancies

NCT ID NCT07178652

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study looks at why women who get pregnant using donated eggs have a higher chance of developing preeclampsia, a serious pregnancy complication. Researchers will collect cheek swabs from mothers, children, and egg donors to analyze specific gene combinations (HLA-C and KIR). By comparing those who developed preeclampsia to those who did not, they hope to identify genetic patterns that increase risk. The goal is to better understand the immune system's role in these pregnancies, not to test a new treatment.

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