New DNA test aims to predict bloodstream infections in kids with cancer
NCT ID NCT03226158
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study at St. Jude Children's Research Hospital is testing whether a next-generation DNA test can predict bloodstream infections in children and teens with cancer who are at high risk. Current methods often detect infections too late, leading to severe illness or death. The goal is to see if this test can spot infection early, so doctors can give the right antibiotics sooner and reduce the use of broad-spectrum drugs that fuel antibiotic resistance. About 160 participants are being followed to measure how accurate the test is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
next generation sequencing (DNA test) of pathogens
What this could lead to
If successful, this could lead to a way to predict bloodstream infections days before they become dangerous, allowing doctors to start targeted antibiotics earlier and avoid broad-spectrum drugs.
What could go wrong
This is an early-stage study focused on measuring how accurate the test is, not yet proving it improves outcomes. The test may not be sensitive or specific enough in real-world settings.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States