New DNA test aims to predict bloodstream infections in kids with cancer
NCT ID NCT03226158
First seen Jun 25, 2026 · Last updated Jul 21, 2026 · Updated 3 times
Summary
This study at St. Jude Children's Research Hospital is testing whether a next-generation DNA test can predict bloodstream infections in children and teens with cancer who are at high risk. Current methods often detect infections too late, leading to severe illness or death. The goal is to see if this test can spot infection early, so doctors can give the right antibiotics sooner and reduce the use of broad-spectrum drugs that fuel antibiotic resistance. About 160 participants are being followed to measure how accurate the test is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- next generation sequencing (DNA test) of pathogens
- What this could lead to
- If successful, this could lead to a way to predict bloodstream infections days before they become dangerous, allowing doctors to start targeted antibiotics earlier and avoid broad-spectrum drugs.
- What could go wrong
- This is an early-stage study focused on measuring how accurate the test is, not yet proving it improves outcomes. The test may not be sensitive or specific enough in real-world settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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