Can a common steroid stop lung fluid from coming back?

NCT ID NCT07039019

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether the steroid prednisone can prevent recurrent pleural effusions (fluid buildup around the lungs) in people with non-specific pleuritis. Forty adults will be randomly assigned to take prednisone daily for 4 weeks or receive no steroid. The study lasts 6 months and tracks how many people have fluid recurrence and need further procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Prednisone (a corticosteroid)

What this could lead to

If it works, this could point toward a simple treatment to prevent fluid buildup in the lungs for people with non-specific pleuritis.

What could go wrong

This is a very early pilot study with only 40 people, so results may not be conclusive. Corticosteroids also have side effects like weight gain and increased infection risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pleurisy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Mount Sinai Morningside

    RECRUITING

    New York, New York, 10029, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••