Can a common steroid stop lung fluid from coming back?

NCT ID NCT07039019

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tests whether the steroid prednisone can prevent recurrent pleural effusions (fluid buildup around the lungs) in people with non-specific pleuritis. Forty adults will be randomly assigned to take prednisone daily for 4 weeks or receive no steroid. The study lasts 6 months and tracks how many people have fluid recurrence and need further procedures.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Prednisone (a corticosteroid)
What this could lead to
If it works, this could point toward a simple treatment to prevent fluid buildup in the lungs for people with non-specific pleuritis.
What could go wrong
This is a very early pilot study with only 40 people, so results may not be conclusive. Corticosteroids also have side effects like weight gain and increased infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mount Sinai Hospital

    RECRUITING

    New York, New York, 10029, United States

  • Mount Sinai Morningside

    RECRUITING

    New York, New York, 10029, United States