Simple blood test uncovers rare diseases behind mysterious enlarged spleens

NCT ID NCT05641103

First seen Mar 01, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study tested a simple blood spot test to find two rare genetic diseases (Gaucher and ASMD) in 122 adults with an unexplained enlarged spleen or who had their spleen removed for unknown reasons. The goal was to see how common these diseases are in this group. The test measures enzyme activity and genetic markers from a dried blood drop.

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Contacts and locations

Locations

  • CAU Salamanca

    Salamanca, Salamanca, Spain

  • Complejo Hospitalario Universitario La Coruña - CHUAC

    A Coruña, La Coruña, Spain

  • Complejo Hospitalario Universitario de Santiago - CHUS

    Santiago de Compostela, La Coruña, Spain

  • Hospital General Universitario de Alicante

    Alicante, Alicante, Spain

  • Hospital Universitario Central de Asturias - HUCA

    Oviedo, Principality of Asturias, Spain

  • Hospital Universitario Joan XXIII

    Tarragona, Tarragona, Spain

  • Hospital Universitario Juan Ramón Jiménez

    Huelva, Huelva, Spain

  • Hospital Universitario La Princesa

    Madrid, Madrid, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, Lugo, Spain

  • Hospital Universitario de Badajoz

    Badajoz, Badajoz, Spain

  • Hospital Universitario de Cabueñes

    Gijón, Principality of Asturias, Spain

  • Hospital Universitario de Galdácano

    Galdakao, Vizcaya, Spain

  • Hospital Vall d'Hebron

    Barcelona, Barcelona, Spain

  • Hospital de Poniente

    El Ejido, Almería, Spain

Conditions

Explore the condition pages connected to this study.