Brain scans may predict who faces memory loss after radiation

NCT ID NCT04638478

Ongoing Knowledge-focused Sponsor: Maastricht Radiation Oncology Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study is testing whether advanced MRI scans can predict which meningioma patients will experience cognitive decline after radiotherapy. Researchers will follow 67 patients for two years, using cognitive tests and brain imaging before and after treatment. The goal is to identify brain regions most sensitive to radiation damage, so future treatments can be tailored to reduce side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify patients at risk for memory and thinking problems after brain radiation, leading to more personalized and safer treatment plans.
What could go wrong: This is a small, early-stage observational study (67 participants) that aims to find patterns, not test a treatment. It may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

meningioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENINGIOMA

Contacts and locations

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Locations

Maastricht Radiation Oncology

Maastricht, Limburg, 6202 AZ, Netherlands

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