Could custom dosing of a lupus drug help kids with kidney disease?
NCT ID NCT05538208
First seen Mar 24, 2026 · Last updated May 11, 2026 · Updated 7 times
Summary
This study compares two ways of giving the drug mycophenolate mofetil (MMF) to children and teens with lupus nephritis, a kidney disease caused by lupus. One method uses the child's body size to set the dose, while the other adjusts the dose based on drug levels in the blood. The goal is to see if the personalized approach leads to better kidney remission after 26 weeks. About 105 participants aged 8 to under 21 will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Locations
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Akron Children's Hospital
RECRUITINGAkron, Ohio, 44307, United States
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Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60614, United States
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Baylor College of Medicine Pediatric Immunology Allergy Rheumatology
RECRUITINGHouston, Texas, 77030, United States
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Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital at Montefiore
RECRUITINGNew York, New York, 10467, United States
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Children's Wisconsin/Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45223, United States
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Emory Children's Center
RECRUITINGAtlanta, Georgia, 30322, United States
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10021, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
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Seattle Children's Hospital/University of Washington
RECRUITINGSeattle, Washington, 98105, United States
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University Hospitals Cleveland Medical Center
RECRUITINGCleveland, Ohio, 44106, United States
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94518, United States
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University of Chicago Medicine- Comer Children's
RECRUITINGChicago, Illinois, 60637, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27599, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84132, United States
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Washington University in St. Louis School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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