Zapping nerves before knee surgery may cut pain — trial puts it to the test
NCT ID NCT07727551
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether a nerve-blocking procedure called genicular nerve radiofrequency ablation, done two to six weeks before total knee replacement, can reduce postoperative pain and improve function. The study includes adults aged 18 to 60 who are scheduled for knee replacement and have certain risk factors like obesity, diabetes, or chronic pain. Participants are randomly assigned to receive the nerve block or not, and their pain and mobility are tracked after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiofrequency ablation of the genicular nerve
- What this could lead to
- If it works, this could offer a way to reduce pain and speed up recovery after knee replacement surgery.
- What could go wrong
- This is a small early-stage trial, so results may not apply to everyone. The procedure carries risks like nerve damage or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Iris South Hospitals
RECRUITINGBrussels, 1050, Belgium
More trials for these conditions
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