Short drug combo before surgery may prime immune system against aggressive breast cancer

NCT ID NCT04427293

First seen Jan 09, 2026 · Last updated May 15, 2026 · Updated 13 times

Summary

This study is for people with early-stage triple-negative breast cancer who are scheduled for surgery. Before surgery, they will receive two drugs: lenvatinib (taken daily for 7 days) and one dose of pembrolizumab (given by IV). The goal is to see if this short treatment can increase immune cells inside the tumor, which may help the body fight the cancer. The study is small (12 participants) and is in an early phase to check how well the approach works.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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