Potassium power: can supplements tame high blood pressure?
NCT ID NCT05758142
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how different amounts of potassium supplements affect blood pressure in adults with high blood pressure. Researchers aimed to find the best potassium level to help lower blood pressure. The study was stopped early and included 25 participants.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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25 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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May 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men or women aged \>18 years of any race/ethnicity * Elevated BP or hypertension at screening (untreated office systolic BP 120-159 and diastolic BP \<100 mm Hg) * Willing and able to provide informed consent Exclusion Criteria: * Medical condition in which potassium supplementation is contraindicated: history of heart failure, myocardial infarction, stroke, cardiac arrythmia, chronic kidney disease or estimated glomerular filtration rate \<60 ml/min/1.73 m\^2, diabetes or non-fasting glucose \>200 mg/dL, major depressive disorder (PHQ-9 score ≥15), psychosis, ulcer diseases including esophageal-gastric ulcer, malignancy in the past 5 years, liver disease, organ transplant, Addison's disease (adrenal insufficiency) * Use of medications which may alter serum potassium levels or in which potassium supplementation is contraindicated: antihypertensive agents, antihistamines, antiparkinson agents, antimuscarinic agents, antipsychotics, muscle relaxants, systemic corticosteroids, or chronic use of non-steroidal anti-inflammatory drugs * Serum potassium ≥5.0 mEq/L * Metabolic acidosis * Consumption of \>85th percentile of usual potassium intake among US adults (\>3,750 mg/day) * For women, current pregnancy, breastfeeding, or plans to become pregnant during the study * Consumption of ≥21 alcoholic beverages per week or consumption of ≥6 beverages per occasion * Current or planned residence making it difficult to meet trial requirements or travel to the study site * Current participation in another intervention or pharmaceutical trial * Unable or unwilling to complete 24-hour BP or urinary sample collection * Other concerns regarding ability to meet trial requirements, at the discretion of the investigators or staff
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tulane University Office of Health Research
New Orleans, Louisiana, 70112, United States
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