Can a breathing mask keep severely obese patients off the ventilator?

NCT ID NCT05918575

First seen Oct 31, 2025 · Last updated Apr 29, 2026 · Updated 24 times

Summary

This study looks at whether using noninvasive breathing support right after removing the breathing tube can help severely obese patients avoid needing the tube again. About 20% of these patients currently require re-intubation, which raises risks of pneumonia, longer hospital stays, and death. The trial will enroll 250 adults with a BMI of 40 or higher who have been on a ventilator for at least 24 hours.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Central DuPage Hospital

    NOT_YET_RECRUITING

    Winfield, Illinois, 60190, United States

    Contact Email: •••••@•••••

    Contact

  • Hospital Civil Fray Antonio Alcalde

    RECRUITING

    Guadalajara, Jalisco, 44280, Mexico

    Contact Email: •••••@•••••

    Contact

  • McGovern Medical School, The University of Texas Health Science Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Email: •••••@•••••

    Contact

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

Conditions

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