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AFib ablation study halted early – what it means for patients

NCT ID NCT06364215

Terminated Disease control Sponsor: Jorge Romero Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of heart ablation for people with paroxysmal atrial fibrillation (AFib). One group received standard pulmonary vein isolation, while the other also had the back wall of the left atrium isolated. Both used a newer technique called pulsed-field ablation. The trial was terminated early, so we don't have full results on which approach works better or is safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pulsed-field ablation (device procedure)
What this could lead to
If successful, this could show that adding posterior wall isolation to standard ablation reduces atrial fibrillation recurrence more than standard ablation alone.
What could go wrong
The trial was terminated, so no definitive conclusions can be drawn. It was also a relatively small, single-center study, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation paroxysmal atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (PAROXYSMAL)

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Corewell Health William Beaumont Hospital

    Royal Oak, Michigan, 48073, United States

  • Doylestown Hospital

    Doylestown, Pennsylvania, 18901, United States

  • Grandview Medical Center

    Birmingham, Alabama, 35243, United States

  • HCA Florida Mercy Hospital

    Miami, Florida, 33133, United States

  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01805, United States

  • Maine Medical Center

    Portland, Maine, 04102, United States

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Methodist Hospital-San Antonio

    San Antonio, Texas, 78229, United States

  • North Shore University Hospital, Northwell Health

    Manhasset, New York, 11030, United States

  • Orion Medical

    Houston, Texas, 77034, United States

  • St. Luke's Boise Medical Center

    Boise, Idaho, 83712, United States

  • St. Vincent's Health System, Inc. d/b/a Ascension St. Vincent's

    Jacksonville, Florida, 32204, United States

  • The Valley Hospital

    Paramus, New Jersey, 07652, United States

  • Trident Medical Center

    Charleston, South Carolina, 29406, United States

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

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