New monitoring method may cut surgery risks by guiding fluid use

NCT ID NCT03828565

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether continuously monitoring central venous oxygen saturation (ScvO2) during major abdominal surgery helps doctors give fluids more precisely, reducing complications. 220 patients over 50 with moderate-to-high surgical risk were randomly assigned to ScvO2-guided care or standard care. The goal was to see if this approach lowers the overall complication score at day 5 after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ScvO2 continuous monitoring with PreSep® system
What this could lead to
If successful, this approach could reduce post-surgery complications by better guiding fluid therapy during major abdominal surgeries.
What could go wrong
This is a completed trial with 220 participants, but the intervention is a monitoring procedure, not a drug, so benefits may be modest and context-dependent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Laurent Zieleskiewicz

    Marseille, PACA, 13354, France