Titanium jaw implant could replace bone grafts in cancer patients

NCT ID NCT00213837

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tested a new porous titanium implant to rebuild the front part of the jaw after it is removed during cancer surgery. The implant is designed to avoid the need for bone grafts taken from elsewhere in the body, which can cause additional pain and complications. Seven adults participated, and the study looked at how well the implant worked and any complications that occurred.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
porous titanium mandibular prosthesis
What this could lead to
If successful, this implant could offer a simpler, safer way to rebuild the jaw after cancer surgery, reducing the need for complex bone grafts.
What could go wrong
This is a very small early-phase trial with only 7 participants, so results may not apply widely. The implant may fail to integrate or cause complications like infection or rejection.

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Conditions

The condition(s) this trial relates to.

otorhinolaryngologic disease Vocal Cord Paralysis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service d'Oto-Rhino-Laryngologie et de Chirurgie Cervico-Faciale, Hôpital de Hautepierre

    Strasbourg, France

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