New hope for kids with rare Muscle-Weakening disease

NCT ID NCT03911505

Summary

This study is testing a new combination drug (cipaglucosidase alfa with miglustat) for children with late-onset Pompe disease, a rare genetic disorder that weakens muscles. The main goal is to see if the treatment is safe and how well it works in children from birth up to 18 years old. It is for kids who have never had enzyme replacement therapy before, as well as those who are already receiving a standard treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Gunma University Hospital

    Gunma, 371-8511, Japan

  • Izumi City General Hospital

    Osaka, Izumi-Shi, 594-0073, Japan

  • Lysosomal and Rare Disorders Research and Treatment Center, Inc.

    Fairfax, Virginia, 22030, United States

  • San Gerardo Hospital

    Monza, 20900, Italy

  • SphinCS GmbH Clinical Science for LSD

    Hochheim am Main, Hesse, 65239, Germany

  • St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

  • Tohoku University Hospital

    Miyagi, 980-8574, Japan

  • Tokyo Women's Medical University

    Tokyo, 162-8666, Japan

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • University of Calgary

    Calgary, Alberta, T3B 6A8, Canada

  • University of Florida Clinical Research Center

    Gainesville, Florida, 32610, United States

  • University of Utah, Clinical and Translational Sciences Institute

    Salt Lake City, Utah, 84108, United States

  • Wolfson Children's Hospital

    Jacksonville, Florida, 32207, United States

  • Women's and Children's Hospital

    North Adelaide, South Australia, 5006, Australia

  • Woodruff Memorial Research Building

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.