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New drug cocktail shows promise for Hard-to-Treat myeloma

NCT ID NCT03731832

Completed Disease control Sponsor: GWT-TUD GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a combination of three drugs (pomalidomide, ixazomib, and dexamethasone) with or without a fourth drug (cyclophosphamide) in 66 adults with multiple myeloma that had come back or stopped responding to treatment. The goal was to see how well the treatment controlled the disease. Participants received the drugs in cycles, and the study checked for tumor shrinkage or stabilization. This is not a cure, as ongoing management is still needed.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

REFRACTORY MULTIPLE MYELOMA

Contacts and locations

Locations

  • Kliniken Ostalb Stauferklinikum Schwäbisch Gmünd

    Mutlangen, 73557, Germany

  • Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main

    Frankfurt am Main, 60590, Germany

  • Klinikum rechts der Isar der TU München / III. Med. Klinik und Poliklinik

    Munich, Bavaria, 81675, Germany

  • Sozialstiftung Bamberg / Klinik am Bruderwald, Zentrum für Innere Medizin, Med. Klinik V, Hämatologie und internistische Onkologie

    Bamberg, 96049, Germany

  • Studienzentrum Onkologie Ravensburg

    Ravensburg, 88212, Germany

  • Universitätsklinikum Jena / Klinik für Innere Medizin II, Abteilung für Hämatologie und internistische Onkologie

    Jena, 07747, Germany

  • Universitätsklinikum Magdeburg A.Ö.R / Klinik für Hämatologie und Onkologie

    Magdeburg, 39120, Germany

  • Universitätsklinikum Münster / Medizinische Klinik A

    Münster, 48149, Germany

  • Universitätsklinikum Ulm / Klinik für Innere Medizin III

    Ulm, 89081, Germany

  • Universitätsklinikum Würzburg

    Würzburg, 97080, Germany

  • phase drei Hämato-Onkologischer Studienkreis am Klinikum Aschaffenburg

    Aschaffenburg, 63739, Germany

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