New hope for hard-to-treat lymphoma: targeted drug combo shows promise

NCT ID NCT04665765

First seen Oct 31, 2025 · Last updated May 10, 2026 · Updated 23 times

Summary

This study tests a new combination of drugs (polatuzumab vedotin plus standard chemotherapy and immunotherapy) as the first treatment after lymphoma returns or doesn't respond. About 41 adults with diffuse large B-cell lymphoma will receive this therapy to see if it can shrink tumors and control the disease. The goal is to improve response rates while monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.