Can your lung bacteria predict antibiotic failure?

NCT ID NCT06916481

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines how the community of bacteria in the lungs (the microbiome) affects how well pneumonia patients respond to antibiotics. Researchers will follow 300 adults with pneumonia, taking samples from the mouth, rectum, and lungs over 90 days. The goal is to see if the initial bacteria profile can predict treatment failure or the rise of antibiotic resistance, potentially leading to more personalized antibiotic choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which pneumonia patients will respond to antibiotics, reducing treatment failures and antibiotic resistance.
What could go wrong: This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results may not apply to all pneumonia patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nosocomial infection pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMMUNITY ACQUIRED OR ACQUIRING HOSPITAL ACQUIRED PNEUMONIA

Contacts and locations

Locations

CHU Nantes
ACTIVE_NOT_RECRUITING

Nantes, France
CHU Nantes - Saint Herblain
NOT_YET_RECRUITING

Nantes, France
CHU Nantes - Saint Herblain
NOT_YET_RECRUITING

Nantes, France
Hospital Beaujon
ACTIVE_NOT_RECRUITING

Clichy, France
Hospital Bichat
RECRUITING

Paris, 75 018, France
Hospital Bichat
ACTIVE_NOT_RECRUITING

Paris, France

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