Can your lung bacteria predict antibiotic failure?
NCT ID NCT06916481
First seen Jan 03, 2026 · Last updated Jun 22, 2026 · Updated 34 times
Summary
This study examines how the community of bacteria in the lungs (the microbiome) affects how well pneumonia patients respond to antibiotics. Researchers will follow 300 adults with pneumonia, taking samples from the mouth, rectum, and lungs over 90 days. The goal is to see if the initial bacteria profile can predict treatment failure or the rise of antibiotic resistance, potentially leading to more personalized antibiotic choices.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Nantes
ACTIVE_NOT_RECRUITINGNantes, France
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CHU Nantes - Saint Herblain
NOT_YET_RECRUITINGNantes, France
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CHU Nantes - Saint Herblain
NOT_YET_RECRUITINGNantes, France
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Hospital Beaujon
ACTIVE_NOT_RECRUITINGClichy, France
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Hospital Bichat
RECRUITINGParis, 75 018, France
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Bichat
ACTIVE_NOT_RECRUITINGParis, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors predict which pneumonia patients will respond to antibiotics, reducing treatment failures and antibiotic resistance.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results may not apply to all pneumonia patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.