New vaccine strategy aims to shield spleenless adults from pneumonia

NCT ID NCT02052154

First seen Nov 20, 2025 · Last updated May 11, 2026 · Updated 18 times

Summary

This study tested a two-step vaccine approach to protect adults who have had their spleen removed from serious pneumococcal infections. Participants received one shot of a conjugate vaccine followed by a second shot of a polysaccharide vaccine two months later. The goal was to see if this combination triggers a strong immune response against nine common pneumonia-causing bacteria strains. The study involved 70 adults and followed them for 36 months.

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Contacts and locations

Locations

  • Service des Maladies Infectieuses et Tropicales - Centre d'Infectiologie Necker-Pasteur, IHU Imagine - Hôpital Necker-Enfants

    Paris, 75015, France

Conditions

Explore the condition pages connected to this study.