New Alzheimer's drug shows promise in Early-Stage trial

NCT ID NCT06750432

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new drug called PMN310 in people with early Alzheimer's disease. The goal is to see if it is safe and if it can reduce signs of the disease in the brain. About 144 participants will receive multiple doses of the drug or a placebo. This is an early-phase trial, so the main focus is safety, but researchers will also look at whether the drug affects Alzheimer's-related biomarkers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease early-onset autosomal dominant Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Memory Research Institute of NJ

    Toms River, New Jersey, 08755, United States

  • Alzheimer's Disease Research Center

    Albany, New York, 12208, United States

  • Alzheimer's Research and Treatment Center

    Stuart, Florida, 34997, United States

  • Alzheimer's Research and Treatment Center

    Wellington, Florida, 33414, United States

  • Brain Matters Research

    Delray Beach, Florida, 33445, United States

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030, United States

  • Charter Research

    Orlando, Florida, 32803, United States

  • Charter Research

    The Villages, Florida, 32162, United States

  • Columbus Memory Center, LLC

    Columbus, Georgia, 31909, United States

  • Conquest Research, LLC

    Winter Park, Florida, 32789, United States

  • Finlay Medical Research

    Miami, Florida, 33126, United States

  • Flourish Research

    Matthews, North Carolina, 28105, United States

  • Gonzalez MD and Aswad MD Health Services, Optimus U Corp

    Miami, Florida, 33135, United States

  • Headlands Eastern MA LLC

    Plymouth, Massachusetts, 02360, United States

  • Healthy Brain Research

    Long Beach, California, 90804, United States

  • Irvine Center for Clinical Research

    Irvine, California, 92614, United States

  • JEM Research Institute

    Atlantis, Florida, 33462, United States

  • Kerwin Medical Center

    Dallas, Texas, 75231, United States

  • Keystone Clinical Studies, LLC

    Plymouth Meeting, Pennsylvania, 19462, United States

  • Neuro Behavioral Clinical Research, Inc.

    North Canton, Ohio, 44720, United States

  • Quantum Laboratories

    Deerfield Beach, Florida, 33442, United States

  • Renstar Medical Research

    Ocala, Florida, 34470, United States