New study aims to unlock the brain chemistry behind severe PMS
NCT ID NCT06704594
First seen May 11, 2026 · Last updated May 24, 2026 · Updated 3 times
Summary
This study looks at how natural brain chemicals change across the menstrual cycle in women with PMDD, a severe form of PMS. Researchers will compare blood levels of certain hormones and brain receptors in 288 women with and without PMDD. They will also test how a low-dose antidepressant affects these measures. The goal is to better understand what causes PMDD and how treatments work.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Reproductive Mental Health Center
RECRUITINGBaltimore, Maryland, 21205, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.