New study probes brain chemistry behind severe PMS
NCT ID NCT06704594
First seen May 11, 2026 · Last updated May 11, 2026
Summary
This study aims to understand why some women develop Premenstrual Dysphoric Disorder (PMDD), a severe form of PMS. Researchers will measure brain-related hormones and proteins in the blood of 288 women with and without PMDD during their menstrual cycle. They will also test how a low-dose antidepressant affects these measures in women with PMDD. The goal is to uncover the biological mechanisms behind PMDD and its treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Reproductive Mental Health Center
RECRUITINGBaltimore, Maryland, 21205, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Virginia
RECRUITINGCharlottesville, Virginia, 22903, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.