New drug shows promise in shrinking lung scars in IPF patients

NCT ID NCT05621252

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 33 times

Summary

This study tested a new drug called PLN-74809 in 10 people with idiopathic pulmonary fibrosis (IPF), a disease that causes lung scarring. The goal was to see if the drug could reduce scarring in the lungs over 12 weeks. Participants took either the drug or a placebo, and doctors used a special imaging scan to measure changes in collagen, a key part of scar tissue.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.