New chemo combo aims to slow tough-to-treat prostate cancer

NCT ID NCT06439225

First seen Nov 18, 2025 · Last updated Apr 24, 2026 · Updated 16 times

Summary

This study tests whether adding a second chemotherapy drug (platinum) to the usual treatment (docetaxel) can slow the growth of advanced prostate cancer that no longer responds to hormone therapy. It is for people whose tumors have certain DNA repair gene changes. About 236 participants will be randomly assigned to receive either docetaxel alone or docetaxel plus platinum. The main goal is to see if the combination helps people live longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allan Blair Cancer Centre

    RECRUITING

    Regina, Saskatchewan, S4T 7T1, Canada

    Contact Phone: •••-•••-••••

  • Arthur J.E. Child Comprehensive Cancer Centre

    RECRUITING

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-••••

  • BCCA - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Phone: •••-•••-••••

  • CHU de Quebec-Hopital l'Enfant-Jesus (HEJ)

    RECRUITING

    Québec, Quebec, G1J 1Z4, Canada

    Contact Phone: •••-•••-••••

  • CHUM-Centre Hospitalier de l'Universite de Montreal

    RECRUITING

    Montreal, Quebec, H2X 3E4, Canada

    Contact Phone: •••-•••-••••

  • Cross Cancer Institute

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

    Contact Phone: •••-•••-••••

  • London Health Sciences Centre Research Inc.

    RECRUITING

    London, Ontario, N6A 5W9, Canada

    Contact Phone: •••-•••-••••

  • Odette Cancer Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-••••

  • Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact Phone: •••-•••-••••

  • Saskatoon Cancer Centre

    RECRUITING

    Saskatoon, Saskatchewan, S7N 4H4, Canada

    Contact Phone: •••-•••-••••

  • The Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

    Contact

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

  • Waterloo Regional Health Network (WRHN)

    RECRUITING

    Kitchener, Ontario, N2G 1G3, Canada

    Contact

  • William Osler Health System

    RECRUITING

    Brampton, Ontario, L6R 3J7, Canada

    Contact

Conditions

Explore the condition pages connected to this study.