New pill could ease strict PKU diet for thousands
NCT ID NCT06971731
Summary
This study is testing a new oral medication called JNT-517 to see if it can safely and effectively lower blood phenylalanine (Phe) levels in adults with PKU. About 120 participants will take either the study drug or a placebo (a pill with no medicine) for the first six weeks, followed by a longer period where everyone receives the active drug. The main goal is to see how much the drug reduces Phe levels, which could help manage the condition.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
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Beatrix Children's Hospital
RECRUITINGGroningen, Netherlands
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Centre Hospitalier Régional Universitaire (CHRU) de Tours - Hôpital Bretonneau
RECRUITINGTours, France
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Hospital Clinico Universitario de Santiago de Compostela
RECRUITINGSantiago de Compostela, Spain
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, Spain
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Mater Health - Mater Hospital Brisbane
RECRUITINGSouth Brisbane, 4104, Australia
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Nihon University Hospital
RECRUITINGChiyoda-ku, Japan
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Oregon Health and Science University
RECRUITINGPortland, Oregon, 97239, United States
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Osaka Metropolitan University Hospital
RECRUITINGOsaka, Japan
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Pomorski Uniwersytet Medyczny w Szczecinie
RECRUITINGSzczecin, Poland
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Royal Adelaide Hospital
RECRUITINGAdelaide, 5000, Australia
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Royal Melbourne Hospital
RECRUITINGParkville, Australia
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Universitair Medisch Centra (AMC)- Amsterdam
RECRUITINGAmsterdam, Netherlands
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University of California Los Angeles (UCLA) School of Medicine
RECRUITINGLos Angeles, California, 90024, United States
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University of Florida (UF) Health Shands Hospital
RECRUITINGGainesville, Florida, 32608, United States
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University of Pittsburgh Medical Center (UPMC) - Children's Hospital of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15201, United States
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University of Texas Health (UTHealth) Science Center at Houston
RECRUITINGHouston, Texas, 77030-1501, United States
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University of Texas Southwestern
RECRUITINGDallas, Texas, 75390, United States
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Utah Health - The University of Utah Hospital
RECRUITINGSalt Lake City, Utah, 84112, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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Conditions
Explore the condition pages connected to this study.