Experimental cancer combo trial halted early
NCT ID NCT05147350
First seen Jan 04, 2026 · Last updated May 13, 2026 · Updated 16 times
Summary
This early-stage study tested a new drug (RP-6306) combined with standard chemotherapy (FOLFIRI) in 38 adults with advanced solid tumors, including colorectal, GI, and esophageal cancers that had stopped responding to other treatments. The main goals were to check safety, find the best dose, and see if the combo could shrink tumors. The study was terminated early, so results are limited.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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# 2001, Princess Margaret Cancer Centre
Toronto, Ontario, ON M5G 2M9, Canada
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# 3003, Sarah Cannon Research Institute
London, W1G 6AD, United Kingdom
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# 5002, South Texas Accelerated Research Therapeutics
Madrid, Spain
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# 5003, Hospital Universitario HM Sanchinarro
Madrid, Spain
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#1001, The University of Texas M.D. Anderson Cancer Center
Houston, Texas, 77030, United States
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#1008, Columbia University
New York, New York, 10032, United States
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#1013, The University of Utah, Huntsman Cancer Center
Salt Lake City, Utah, 84112, United States
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#1019, UCLA, Westwood Cancer Center
Los Angeles, California, 90095, United States
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#1022, Moffitt Cancer Center
Tampa, Florida, 33612, United States
Conditions
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