New hope for fighting crippling sleepiness in rare genetic disorder
NCT ID NCT04257929
Summary
This study is testing whether a medication called pitolisant can safely reduce excessive daytime sleepiness in people with Prader-Willi syndrome (PWS), a rare genetic disorder. About 65 patients aged 6 to 65 will receive either the drug or a placebo for 11 weeks, with an option for long-term treatment afterward. Researchers will measure changes in sleepiness, behavior, and caregiver burden to see if the treatment helps.
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Contacts and locations
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Locations
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Ann and Robert H Lurie Children's Hospital
Chicago, Illinois, 60611, United States
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CTI
Cincinnati, Ohio, 45212, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Johns Hopkins School of Medicine
Baltimore, Maryland, 21205, United States
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Nemours Alfred I duPont Hospital for Children
Wilmington, Delaware, 19803, United States
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Rady Children's Hospital - San Diego
San Diego, California, 92123, United States
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Road Runner Research
San Antonio, Texas, 78249, United States
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Santa Monica Clinical Trials
Santa Monica, California, 90404, United States
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Sleep Medicine Specialists of California
San Ramon, California, 94583, United States
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Texas Children's Hospital/Baylor College of Medicine
Houston, Texas, 77030, United States
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University of Florida College of Medicine
Gainesville, Florida, 32608, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68114, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States
Conditions
Explore the condition pages connected to this study.