New leukemia pill goes Head-to-Head with standard treatment in major trial

NCT ID NCT05254743

Recruiting now Disease control Sponsor: Loxo Oncology, Inc. Source: ClinicalTrials.gov ↗

Summary

This study aims to compare the effectiveness and safety of a new oral drug called pirtobrutinib against the standard drug ibrutinib for adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). It will enroll about 660 participants, some who have had prior treatment and some who are newly diagnosed. The goal is to see if the new drug can better control the cancer and cause fewer side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

9 Eylul University Hospital
ACTIVE_NOT_RECRUITING

Balçova, 35100, Turkey (Türkiye)
AIDPORT Sp. z o.o.
RECRUITING

Skórzewo, 60-185, Poland

Contact
Acıbadem Maslak Hastanesi
COMPLETED

Istanbul, 34457, Turkey (Türkiye)
Affiliated Cancer Hospital of Xinjiang Medical University
ACTIVE_NOT_RECRUITING

Ürümqi, 830000, China
Alexander Fleming
RECRUITING

Ciudad Autónoma de Buenos Aire, C1426ANZ, Argentina

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American Hospital
ACTIVE_NOT_RECRUITING

Istanbul, 34365, Turkey (Türkiye)
American Oncology Partners of Maryland, PA
RECRUITING

Bethesda, Maryland, 20817, United States

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Anhui Provincial Hospital
ACTIVE_NOT_RECRUITING

Hefei, 230001, China
Ankara University Medicine Hospital
RECRUITING

Mamak, 06590, Turkey (Türkiye)

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Azienda Ospedaliera Nazionale Santi Antonio e Biagio e Cesare Arrigo
RECRUITING

Alessandria, 15100, Italy

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Azienda Unita Sanitaria Locale di Reggio Emilia
ACTIVE_NOT_RECRUITING

Reggio Emilia, 42122, Italy
Blood Institute of the Chinese Academy of Medical science
ACTIVE_NOT_RECRUITING

Tianjin, 300020, China
Bristol Haematology and Oncology Centre
RECRUITING

Bristol, BS2 8ED, United Kingdom

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CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia
RECRUITING

Santo André, 09060-650, Brazil

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CHD Vendee
RECRUITING

La Roche-sur-Yon, 85000, France

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CHRU De Tours
RECRUITING

Tours, 37044, France

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CHU de Nantes - Hotel Dieu
RECRUITING

Nantes, 44093, France

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California Cancer Associates for Research and Excellence
ACTIVE_NOT_RECRUITING

San Marcos, California, 92069, United States
Cancer Care Associates of York
ACTIVE_NOT_RECRUITING

York, Pennsylvania, 17403, United States
Cancer Care Manitoba
ACTIVE_NOT_RECRUITING

Winnipeg, R3E 0V9, Canada
Cancer Specialists of North Florida -St Augustine
RECRUITING

Saint Augustine, Florida, 32086, United States

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Castle Hill Hospital
RECRUITING

Cottingham, HU16 5JQ, United Kingdom

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CeCim Biocinetic
ACTIVE_NOT_RECRUITING

Santiago, 8320000, Chile
Centre Antoine Lacassagne
RECRUITING

Nice, 06189, France

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Centre Hospitalier Lyon Sud
RECRUITING

Pierre-Bénite, 69495, France

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Centre Hospitalier Universitaire (Limoges) (CHU DUPUYTREN 1)
RECRUITING

Limoges, 87042, France

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Centre Hospitalier du Mans
RECRUITING

Le Mans, 72000, France

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Centre de Lutte Contre le Cancer - Centre Henri Becquerel Normandie Rouen
RECRUITING

Rouen, 76038, France

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Centro Gaucho Integrado - Mae de Deus Center
RECRUITING

Porto Alegre, 90110270, Brazil

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Centro Integrado de Oncologia de Curitiba
ACTIVE_NOT_RECRUITING

Curitiba, 80810050, Brazil
Centro Integrado de Pesquisa Clinica
RECRUITING

São José do Rio Preto, 15090-000, Brazil

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Centro de Investigaciones Clínicas Viña del Mar (CIC)
ACTIVE_NOT_RECRUITING

Viña del Mar, 2520000, Chile
Chang Bing Show Chwan Memorial Hospital
RECRUITING

Changhua, 710, Taiwan

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Chang Gung Memorial Hospital - Chiayi
ACTIVE_NOT_RECRUITING

Chiayi County, 61363, Taiwan
Clinica Universitaria De Navarra
RECRUITING

Pamplona, 31008, Spain

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Clínica de Nefrología, Urología y Enfermedades Cardiovasculares
RECRUITING

Santa Fe, 3000, Argentina

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Debreceni Egyetem Orvos-es Egészsegtudomanyi Centrum
ACTIVE_NOT_RECRUITING

Debrecen, 4004, Hungary
Dunedin Hospital
ACTIVE_NOT_RECRUITING

Dunedin, 9016, New Zealand
Ege Üniversitesi
ACTIVE_NOT_RECRUITING

Bornova, 35040, Turkey (Türkiye)
Fakultni Nemocnice Ostrava
RECRUITING

Ostrava, 708 52, Czechia

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Fakultni Nemocnice Plzen
RECRUITING

Pilsen, 305 99, Czechia

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Fakultni nemocnice Brno
ACTIVE_NOT_RECRUITING

Brno, 62500, Czechia
Fakultni nemocnice Hradec Kralove
RECRUITING

Hradec Králové, 500 05, Czechia

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Fakultni nemocnice Kralovske Vinohrady
RECRUITING

Prague, 10034, Czechia

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First Affiliated Hosp of College of Med, Zhejiang University
RECRUITING

Hangzhou, 310003, China

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Florida Cancer Specialists
ACTIVE_NOT_RECRUITING

Fort Myers, Florida, 33916-2233, United States
Florida Cancer Specialists East
ACTIVE_NOT_RECRUITING

West Palm Beach, Florida, 33401, United States
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China

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Fundação Pio XII - Hospital de Câncer de Barretos
RECRUITING

Barretos, 14784400, Brazil

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Gazi University Faculty of Medicine
ACTIVE_NOT_RECRUITING

Ankara, 6500, Turkey (Türkiye)
Gemeinschaftspraxis für Hämatologie und Onkologie (Gefos)
ACTIVE_NOT_RECRUITING

Dortmund, 44309, Germany
Guangxi Medical University Affiliated Tumor Hospital
ACTIVE_NOT_RECRUITING

Nanning, 530021, China
HOPE Centre
ACTIVE_NOT_RECRUITING

Leicester, LE1 5WW, United Kingdom
Hadassah Medical Center
ACTIVE_NOT_RECRUITING

Jerusalem, 9112001, Israel
Hainan General Hospital
ACTIVE_NOT_RECRUITING

Haikou, 570311, China
Hanusch Krankenhaus
ACTIVE_NOT_RECRUITING

Vienna, 1140, Austria
Hematology Oncology Clinic
ACTIVE_NOT_RECRUITING

Baton Rouge, Louisiana, 70809, United States
Hemocentro Unicamp
ACTIVE_NOT_RECRUITING

Campinas, 13083-878, Brazil
Hopital de L'Enfant Jesus
RECRUITING

Québec, G1J 1Z4, Canada

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Hopital de la Pitie Salpetriere
RECRUITING

Paris, 75651, France

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Hospital BP
RECRUITING

São Paulo, 01321-001, Brazil

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Hospital Clinic de Barcelona
ACTIVE_NOT_RECRUITING

Barcelona, 08036, Spain
Hospital Costa Del Sol
ACTIVE_NOT_RECRUITING

Marbella, 29600, Spain
Hospital De Navarra
ACTIVE_NOT_RECRUITING

Pamplona, 31008, Spain
Hospital Duran i Reynals
ACTIVE_NOT_RECRUITING

L'Hospitalet de Llobregat, 08908, Spain
Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer
RECRUITING

Curitiba, 81520060, Brazil

Contact Phone: •••-•••-••••

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Hospital Privado De Comunidad
ACTIVE_NOT_RECRUITING

Mar del Plata, 7600, Argentina
Hospital Santa Marcelina
RECRUITING

São Paulo, 08270-120, Brazil

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Hospital Universitari Vall d'Hebron
ACTIVE_NOT_RECRUITING

Barcelona, 8035, Spain
Hospital Universitario Infanta Leonor-INTERNAL MED
ACTIVE_NOT_RECRUITING

Madrid, 28031, Spain
Hospital Universitario Marqués de Valdecilla
RECRUITING

Santander, 39008, Spain

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Hospital Universitario Puerta de Hierro Majadahonda
ACTIVE_NOT_RECRUITING

Majadahonda, 28222, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, 28034, Spain

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Hospital Universitario Virgen Del Rocio
ACTIVE_NOT_RECRUITING

Seville, 41013, Spain
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain

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Hospital Uopeccan - Centro de Pesquisa Clinica
ACTIVE_NOT_RECRUITING

Cascavel, 85806-300, Brazil
Hospital da Clinicas da Faculdade de Medicina da USP
RECRUITING

São Paulo, 05403-000, Brazil

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Hospital de Clínicas de Ribeirão Preto
RECRUITING

Ribeirão Preto, 14051-140, Brazil

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Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08025, Spain

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Hunan Cancer Hospital
ACTIVE_NOT_RECRUITING

Changsha, 410013, China
Hôpital de Pontchaillou
RECRUITING

Rennes, 35033, France

Contact Phone: •••-•••-••••

Contact
IRCCS Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy

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Inje Univ Busan Paik Hospital
RECRUITING

Busan, 47392, South Korea

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Inmunocel
ACTIVE_NOT_RECRUITING

Santiago, 7580206, Chile
Instituto do Câncer - Hospital São Vicente de Paulo
RECRUITING

Passo Fundo, 99010090, Brazil

Contact Phone: •••-•••-••••

Contact
Istanbul University Istanbul Medicine Faculty
ACTIVE_NOT_RECRUITING

Faith, 34732, Turkey (Türkiye)
Istituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy

Contact Phone: •••-•••-••••

Contact
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
RECRUITING

Meldola, 47014, Italy

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Contact
Jiangxi Provincial Cancer Hospital
ACTIVE_NOT_RECRUITING

Nanchang, 330029, China
KO-MED Centra Kliniczne
ACTIVE_NOT_RECRUITING

Biała Podlaska, 21500, Poland
Kelsey Research Foundation
ACTIVE_NOT_RECRUITING

Houston, Texas, 77025, United States
Klinika Hematoonkologii i Transplantacji Szpiku,Samodzielny Publiczny Szpital Kliniczny Nr 1
ACTIVE_NOT_RECRUITING

Lublin, 20-081, Poland
Koo Foundation Sun Yan-Sen Cancer Center
RECRUITING

Taipei, 112, Taiwan

Contact Phone: •••-•••-••••

Contact
Kumamoto University Hospital
ACTIVE_NOT_RECRUITING

Kumamoto, 860-8556, Japan
Lumi Research
RECRUITING

Kingwood, Texas, 77339, United States

Contact
Markusovszky Egyetemi Oktatokorhaz
ACTIVE_NOT_RECRUITING

Szombathely, 9700, Hungary
Medical Oncology Associates, PS
RECRUITING

Spokane, Washington, 99208, United States

Contact Phone: •••-•••-••••

Contact
Middlemore Clinical Trials
ACTIVE_NOT_RECRUITING

Papatoetoe, 2025, New Zealand
Momentum Clinical Research
ACTIVE_NOT_RECRUITING

Newtown, 6242, New Zealand
MultiCare Health System Institute for Research and Innovation
ACTIVE_NOT_RECRUITING

Spokane, Washington, 99218, United States
National Cheng-Kung Uni. Hosp.
ACTIVE_NOT_RECRUITING

Tainan, 704, Taiwan
One Clinical Research
ACTIVE_NOT_RECRUITING

Nedlands, 6009, Australia
Onkologische Gemeinschaftspraxis / BAG
RECRUITING

Dresden, 01307, Germany

Contact Phone: •••-•••-••••

Contact
Pacific Cancer Medical Center, Inc
RECRUITING

Anaheim, California, 92801, United States

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Policlinico Sant'Orsola Malpighi
ACTIVE_NOT_RECRUITING

Bologna, 40138, Italy
Pratia MCM Krakow
RECRUITING

Krakow, 30-510, Poland

Contact Phone: •••-•••-••••

Contact
Pratia Onkologia Katowice
RECRUITING

Katowice, 40519, Poland

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Prisma Health Cancer Institute
ACTIVE_NOT_RECRUITING

Greenville, South Carolina, 29605, United States
Royal Victoria Hospital-Montreal
TERMINATED

Montreal, H3A 1A1, Canada
Samsung Medical Center
ACTIVE_NOT_RECRUITING

Seoul, 06351, South Korea
Sarah Cannon Research Institute SCRI
RECRUITING

Nashville, Tennessee, 37203, United States

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Seoul National University Hospital
ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
Singleton Hospital
RECRUITING

Swansea, SA2 8QA, United Kingdom

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Sociedad de Investigaciones Médicas Limitada
RECRUITING

Temuco, 4780000, Chile

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Southern Medical University Nanfang Hospital
ACTIVE_NOT_RECRUITING

Guangzhou, 510515, China
St Bartholomew's Hospital
ACTIVE_NOT_RECRUITING

London, EC1A 7BE, United Kingdom
St. Vincent Frontier Cancer Center
RECRUITING

Billings, Montana, 59102, United States

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Stanford School of Medicine-Cancer Clinical Trials Office
RECRUITING

Palo Alto, California, 94305, United States

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Sun Yat-sen University Cancer Center
RECRUITING

Guangzhou, 510060, China

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Szpital Uniwersytecki nr 1 im. Antoniego Jurasza
ACTIVE_NOT_RECRUITING

Bydgoszcz, 85-168, Poland
TOI Clinical Research
RECRUITING

Cerritos, California, 90703, United States

Contact Phone: •••-•••-••••

Contact
Tel Aviv Sourasky Medical Center
ACTIVE_NOT_RECRUITING

Tel Aviv, 6423906, Israel
The Catholic University of Korea-Seoul St. Mary's Hospital
ACTIVE_NOT_RECRUITING

Seocho-Gu, 06591, South Korea
The Fourth Affiliated Hospital Zhejiang University School of Medicine
ACTIVE_NOT_RECRUITING

Yiwu, 322000, China
The Perth Blood Institute
RECRUITING

West Perth, 6005, Australia

Contact
The Second Affiliated Hospital of Zhejiang University School of Medicine
ACTIVE_NOT_RECRUITING

Hangzhou, 310009, China
The Second Hospital of Anhui Medical University
RECRUITING

Hefei, 231200, China

Contact Phone: •••-•••-••••

Contact
The Second Xiangya Hospital of Central South University
ACTIVE_NOT_RECRUITING

Changsha, 410011, China
Tianjin Medical University General Hospital
ACTIVE_NOT_RECRUITING

Tianjin, 300052, China
Tulane Cancer Center Office of Clinical Research
ACTIVE_NOT_RECRUITING

New Orleans, Louisiana, 70112, United States
Union Hospital Tongji Medical College Huazhong University of Science and Technology
ACTIVE_NOT_RECRUITING

Wuhan, 430022, China
Universitaetsklinikum Carl Gustav Carus an der TU Dresden, Medizinische Klinik und Poliklinik 1
ACTIVE_NOT_RECRUITING

Dresden, 01307, Germany
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
RECRUITING

Leuven, 3000, Belgium

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Universitätsklinikum Ulm
ACTIVE_NOT_RECRUITING

Ulm, 89075, Germany
Uniwersytecki Szpital Kliniczny Klinika
RECRUITING

Wroclaw, 50-367, Poland

Contact Phone: •••-•••-••••

Contact
Uniwersyteckie Centrum Kliniczne
ACTIVE_NOT_RECRUITING

Gdansk, 80-952, Poland
Upeclin - Unidade de Pesquisa Clínica da Faculdade de Medicina de Botucatu - UNESP
RECRUITING

Botucatu, 18618-687, Brazil

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VITAZ
RECRUITING

Sint-Niklaas, B-9100, Belgium

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Virginia Cancer Institute
RECRUITING

Richmond, Virginia, 23230, United States

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Contact
Vseobecna fakultni nemocnice v Praze
ACTIVE_NOT_RECRUITING

Prague, 12808, Czechia
Waikato Hospital
ACTIVE_NOT_RECRUITING

Hamilton, 3204, New Zealand
Western Health, Sunshine Hospital
ACTIVE_NOT_RECRUITING

St Albans, 3021, Australia
Wu Han Tongji Hospital
ACTIVE_NOT_RECRUITING

Wuhan, 430030, China
Yamagata University Hospital
RECRUITING

Yamagata, 990-9585, Japan

Contact Phone: •••-•••-••••

Contact

Conditions

Explore the condition pages connected to this study.

CHRONIC LYMPHOCYTIC LEUKEMIA LEUKEMIA, B-CELL LEUKEMIA, LYMPHOCYTIC SMALL LYMPHOCYTIC LYMPHOMA