New drug duo takes on Hard-to-Treat leukemia

NCT ID NCT06466122

First seen Mar 21, 2026 · Last updated May 14, 2026 · Updated 7 times

Summary

This study tests whether combining two targeted drugs, pirtobrutinib and venetoclax, can eliminate cancer cells in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose disease got worse despite taking standard BTK inhibitors. About 30 adults whose cancer is still detectable in blood or marrow will receive the combination. The main goal is to see if the treatment can make cancer undetectable in both blood and bone marrow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.